I have touched on this subject in several blogs. One large category of GDD is the individual has a pre-existent Tcell dysregulation condition which predisposes then to acquiring GDD. The types of Tcell dysregulation change in populations with changes in behavior, endemic infections, and pollutants. To illustrate another disease that has experienced this shifting demographics: hepatocellular cancer. Disease afflicting the liver directly is the primary underlying cause. In Nort