If you have to get a GBCA-enhanced MRI and are nervous about toxicity. Here is brief advice I just gave to someone: GDD is relatively rare, so your absolute risk is low. That said, make sure you are relatively well hydrated before the study and afterwards... but do not overdo it. Do not over exercise before or after, do not take any high potency drugs like antibiotics - if you are unavoidably on them, then delay MRI. Essentially you want to avoid anything that may throw off t
We have just now been able to witness what happened, what didn't happen, with police in the Uwalde school. The sickening vision of police hiding some distance away from a classroom while small children were slaughtered by a lone gunman. How could this happen, Very simple: cowardice. Cowardice is the most common impulse of most humans when confronted with a terrible challenge. It is however horrifying when one sees it in regards to police doing nothing when small children are
An important preface to this blog is that in my opinion rape involving the penis of the perp entering a woman's vagina should have no statute of limitations, and rapes that had been covered-up in the past by universities should be re-opened, especially if the victim was by some measure further traumatized by the conduct of the university to undermine her. The administrators who were part of the cover-up should face consequences including being sued and prison-time. Rape invol
I consulted with an expert on molecular pharmacy, Michael Jay, PhD, about AN-DTPA and toxicity, and this is what he sent back to me: The AN-DTPA kit is used to prepare 99mTc-DTPA by reacting DTPA with 99mTc-pertchnetate (the product of a 99Mo/99mTc generator) in the presence of tin (Sn) ions. Sn is used to reduce the unreactive 99mTc-pertchnetate to the highly reactive 99mTc(+4) oxidation state which then binds with DTPA. The specific activity (mCi/mg) of 99mTc-pertchnetate
Immune-mediated inflammatory diseases (IMIDs) is a term that encompasses auto-immune disease, auto-inflammatory disease, and diseases that are inflammatory in nature with a known cause. The reality is everything does have a cause, it is just whether we know what it is or not. We do know what causes GDD, that is what many of my blogs are on: it is gadolinium (Gd). To rehash some points mentioned in prior blogs, fundamentally any substance/element that we come into contact with
I was notified by a couple of close collaborators in the GDD sufferer community that a great panic has arisen because AN-DTPA was uncovered on Drugs.com and horrible side effects were described, and therefore was Ca-/Zn-DTPA also dangerous. This reveals at its core one of the issues I have faced in dealing with panics by non-experts about everything. Starting with, from my colleagues in Radiology and the formal medical community, GDD does not exist, GBCAs are perfectly safe.
If you have GDD and are getting DTPA chelation (which is the optimal chelation available at the present time and the only one I use and recommend), you really have to commit to atleast 5 chelation sessions spaced 1-4 weeks apart. Many patients who follow this and have had 1 GBCA injection, and often fewer than 3, will achieve atleast 80% improvement, which is what I aim for. The plan is they recover the rest of the way on their own, with their immune system calming down on i
I I am a GI radiologist and a body MRI expert... and yet I have never liked the subject of feces, nor the anal canal. A number of GDD sufferers have used activated charcoal or zeolyte to aid them in their quest to remove Gd. Some have sent samples off for testing to labs such as Doctors Data.. I am not prepared for my clinic to do that. I have considered that bowel removal agents were a fool's errand for most GBCAs - but maybe I have been wrong. I have seen a report from an i