DTPA Chelation. The Science behind it.

I had been compelled to write a description on chelation on Reddit, because of gross misinformation that a competitor had published on it. Misinformation left unchecked then may be considered correct information. Hopefully I do not have to do this too often, So far I have been polite and not described issues I have with their research, which in contrast are real issues. However to the present time, I have considered any one who writes on issues with GBCAs that benefit patients I see the value in that. It is the height of folly, that happens too often with humans for Lilliputians to fight each other, when there is a giant antagonist in the room. To attack what I do actually attacks not only chelation but also the entire subject of GDD, which does the work for the medico-industrial complex. It does amaze me that people can be so ignorant as not to recognize that. II think t simply reflects a perverse form of jealousy.

Here is Part 1 of the Reddit post. I post it here because it is a nice succinct description.

About Chelation. The science behind it.

There is clearly lack of understanding about chelation. This includes in individuals who actually perform it. I primarily work with chelation for individuals who suffer from Gadolinium Toxicity/ Gadolinium Deposition Disease (GDD), but with experience the same principles apply to most if not all heavy metals.

To start with the simple but powerful observations.

1. If you suffer from Gd toxicity the most obvious and direct treatment is to remove what is making you sick. That removal is chelation.

2. Object determination that it works is to measure 24 hour urine immediately pre- and immediately post/ chelation. We do this routinely with Gd, but this should be done for chelation if all heavy metals.

3. The individual is sick from Gd, we chelate them and show that Gd is removed with 24 hour urine studies, and the majority of subjects get better.

It virtually is more clear than almost any other treatment in medicine.

I will finish this posting with a little of the science, and will expand in the future.

This is what makes it solid science, and to the present time even practitioners of chelation for various metals do not full appreciate… as yet.

There are two critical properties that must be known to perform optimal scientific chelation:

1. What is the log stability constant (aka thermodynamic stability) of the chelator for heavy metal in question. For DTPA and Gd it is 22.. for EDTA and Gd is 17. This translates to a 300,000 greater stability of Gd with DTPA. My opinion is a stability of 20 makes the chelator a good chelator for a metal.

2. It has to work in vivo in humans. This is where the 24 hour urines measures for Gd or other heavy metals pre and post chelation come in.

That is enough for this post. I will clear up finally one other misinformation. The stability of Calcium with DTPA is 6. This makes the stability of Gd with DTPA ten quadrillion times greater than Ca with DTPA.

Only individuals who really know about anything should talk about them. Otherwise you are hearing opinions unconfounded by knowledge. This can be dangerous.

Richard Semelka, MD