Gadolinium movements. A brief repetition.

A small amount of Gd from a GBCA administration remains present in the body for a lifetime, if not removed with chelation. For most people when the Gd is from MR contrast, it seems to be ok.

Gd is eliminated in urine spontaneously for at least 90 days, but there is still a fair amount of Gd left in the body, it is now all deposited in tissues. I estimate 10% at 3 months and 1-2% at 1 year, with little spontaneous removal after that (1% of the total each year).

Gd does not come out like sand trickling down in an hour glass, but some comes out in chunks like icebergs in a glacier, and the elimination profile is probably  a combination. This explains in part why measured of Gd in 24 hr urine post chelation does not follow a simple linear decrease.

RS