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GDD and Digestive System Motility Disorders. Chapter 1. Constipation.



Digestive system motility disorders are common in Gadolinium Deposition Disease (GDD). The digestive system may suffer from hypomotility (slow bowel motion/peristalsis) or hypermotility (fast bowel motion/peristalsis). There are multiple effects that Gd has on the digestive tract: electrical conduction dysfunction, direct muscle effect on actin/myosin, hormone dysfunction, and likely many more.

This chapter deals with constipation (hypomotility of the colon). Probably electrical conduction interference and direct muscle function disruption are the principal effects. Constipation is the most common digestive system dysfunction. Severity ranges from mild hypomotility to near complete atonic (no motion) colon, a paralytic ileus.

Although the primary treatment for GDD is Gd removal, effective restoration of bowel peristalsis takes at least 3 chelation sessions/ 3 months, and it is often imperative to specifically address constipation as well. Many organ / system dysfunction I recommend letting chelation sort things out for 5 or 10 chelation sessions, a number of digestive system dysfunctions should be treated right away, so major health injury does not occur.

Treatment is listed below in order of increasing severity:


Mild constipation

  1. regular warm prune juice.

  2. regular celery juice.

  3. regular coffee

  4. regular metamucil.

  5. other food substances that causes colon evacuation in you (eg: spicy food)


Moderate constipation

  1. additions to above, which can continue.

  2. daily miralax powder (17 grams in 8 oz water).

  3. Senna-docusate (2 tabs at night)

  4. Dulcolax (10 mg rectal suppository) once or twice a day.

  5. warm tap water enema.


Severe constipation

  1. additions to above

  2. manual disimpaction of rectum may be necessary.

  3. tap water enema following disimpaction.



Severe constipation can be an extremely serious condition. This allows bacterial overgrowth in the colon to progress. Colon perforation is rare, but can occur and is a surgical emergency. What can commonly occur is the stagnant overpopulated colon bacteria can release altogether an excessive amount of bacterial endotoxins into the blood stream, which can adversely effect essentially all systems in the body, from bowel to skin to neurological system.



Richard Semelka, MD

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