Perseverance. Foot Notes on that blog.
The foot notes were getting too lengthy and frequent, so rather than distracting from the core message of the Perseverance blog, I am publishing them here separately.
My original writing on chelation was with a set protocol for everyone. Now with considerable experience, I have found that it must be tailored to every particular individual to be done well. Read other blogs on this topic. Lower chelator amount; Ca-DTPA only; Zn-DTPA only; intervals between chelations; knowing the different types of Flare and spacing chelation appropriately; varying steroid amount and method of administration; varying antihistamines; the full range of ancillary treatments.
chelation has to be done correctly. I have written many blogs on it. I start with a low amount of chelator, and work up from there. A relatively high amount of steroid/antihistamine and work down from there. A number of variations can be done. Read all my blogs on that (atleast 3 times). For the future the chelator must have high stability with the metal it is intending to remove. And it must be documented in vivo in humans that it actually can remove it. Until I have written those two sentences I do not know if anyone, including anyone doing chelation, understood those two principle properties.
in general, individuals have undergone MRI with GBCA for a reason. The reason for some people is some other immune dysregulating condition, which may be almost unique and also severe. Correctly done chelation does have benefit for a number of immune dysregulations, either metal removal, steroid use, antihistamine use, or a combination of all. But do not expect that near cure of GDD will cure you of everything else. To get closer to that, read the recent blog on Panacea of Good Health.
I have written the estimate of 5 chelations for each GBCA injection. The more complicating factors, the more chelations required. Chelations must be done carefully and expertly. To do it well does require skill and experience.
Failures of chelation generally reflect failure of doing chelation poorly or not getting enough chelations, and in the poorly category is not managing Flare well. Do not listen to individuals who tell you chelation failed them... They did not have it done correctly, and likely are unaware they did not have it done correctly.. Having it done the way Dr Semelka does it, does not mean they had it done by Dr Semelka. If done by me, two chelations of 10 or more chelations with the other chelations done elsewhere, does not mean it was done by me. Done by me, is all chelations done by me, and at the time points of chelation I have laid out, and the steroids (Goldilocks principle - not too much, not too little). Missing chelation sessions are a set back, but generally not an unrecoverable set back. Using too much steroid in place of getting the correct time point of chelation may be a huge problem.
DTPA chelation is expensive, and despite pt 4, most do need to continue chelation closer to home. But to get best results it has to be done how I would do it. That said, I should add in "or better". One of the reasons I like individuals to go elsewhere is that there may be some variations that would make chelation even better. And ofcourse I would like to do chelation better myself as well.
In other blogs I have described that if I was in the situation of having minimal finances, very sick, felt I could not travel any distance, I would on myself use another chelator that I know works (read pt 1 again) and would be much cheaper, including because it is oral. In that situation absolutely I would take HOPO.
Richard Semelka, MD
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